What is Aprecap used for?

Aprecap capsules are used to prevent nausea and vomiting associated with cancer chemotherapy and are used as combination therapy with other mediations for both highly and moderately emetogenic (vomiting inducing) chemotherapy. Chemotherapy is the use of cytotoxic drugs to kill cancer cells, which grow more rapidly than most normal cells, and nausea and vomiting are common side effects of chemotherapy. Drugs used for chemotherapy stimulate the vomiting reflex that is triggered in the brain. Aprecap capsules block the vomiting reflex and prevent nausea and vomiting induced by these drugs.

How to use Aprecap Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aprecap 125mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

Aprecap 125mg capsule is an antiemetic medication. It blocks the action of a chemical messenger in the brain that may cause nausea and vomiting during treatment with anti-cancer medicines.

How does Aprecap work?

Aprecap capsules contain aprepitant, a selective high-affinity antagonist of the substance P neurokinin 1 (NK₁) receptor. Substance P belongs to a group of neurokinins (NKs), which are small neurotransmitters, or chemical messengers that transmit signals to and from the neurones (brain cells), and it has an important role triggering emesis (vomiting). The vomiting reflex is triggered by stimulation of vomiting centre in the brain, which is a complex area of neuronal networks, by one of several afferent nerve pathways (nerve signals carried to the brain). This can activate vomiting via one of several neurotransmitter receptors. The chemoreceptor trigger zone (CTZ) is one of these afferent nerve pathways and is located in the area postrema of the brain, which is not protected by the blood-brain barrier and therefore, is readily accessible to circulating toxins and drugs.

Aprecap Capsule - Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Aprecap Capsule. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

Anorexia
Constipation
Diarrhoea
Nausea
Aprecap Capsule may also cause side-effects not listed here.

If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.